Epidermolysis Bullosa (EB) encompasses a group of at least 12 seperate genetic diseases of the skin and sometimes the mucous membranes. It is characterised by skin fragility with blister formation occuring spontaneously or following minor trauma. EB can be broadly divided into three major catagories that are recognised accordingly: Simplex, where cell lysis occurs in the epidermis; Junctional, where the separation occurs within the dermal-epidermal junction, and Dystophic, in which the plan of cleavage is below the basement membrane in the dermis. These catagories can be further subtyped based on inheritance and clinical features.